Dolmen takes place in a science fiction universe where humanity has colonized several star systems by using space travel technology and genetic manipulation to adapt to the conditions. The Reviam system is far from the primarily inhabited area of the galaxy, but it has caught the attention of Zoan Corp. It emits radiation that differs from other systems, suggesting the existence of other universes. There is only one planet in this system, named Revion Prime. It is a sci-fi action role-playing game with cosmic horror elements.