Yes, the ProArt PA279CRV works well with a MacPro6.1 (Mac Pro 2013) using DisplayPort, HDMI or USB-C; USB-C also supports power and data but is not Thunderbolt. Make sure to use a compatible cable/output (DisplayPort or USB-C) and check the DisplayPort OSD settings if you encounter recognition problems. Important details: - Supported connections: DisplayPort (2×) and HDMI (2×); USB-C port available for video and up to 96 W PD (not Thunderbolt). - Resolution/refresh: UHD 3840×2160 at 60 Hz, compatible with Mac Pro 6.1 video outputs via DisplayPort or DisplayPort to Thunderbolt adapter. - If using USB-C from newer Apple devices: DisplayPort Stream may need to be set to DisplayPort1.2 in the OSD in some cases. - Multiple monitor compatibility: The ability to connect multiple monitors depends on the graphics capabilities and ports of the Mac Pro; check the maximum number of displays supported by your GPU configuration. I'm not entirely sure if a specific macOS firmware/update is needed for your configuration; if you encounter problems, try - update macOS and monitor firmware, - use a direct DisplayPort cable or Thunderbolt adapter (mini-DisplayPort/DisplayPort port depending on your GPU), - change the DisplayPort Stream setting on your monitor.

The monitor's brightness and volume cannot be controlled directly via the Mac keyboard. Operation is primarily via a 5-way joystick and six buttons on the monitor itself, which can be used to adjust settings such as brightness and volume.

I was able to solve my monitor wake-up problems (up to 30sec to picture) by disabling auto detect on the monitor and setting USB-C as signal input in my example

Try connecting the Macbook directly with the USB-C cable (USB-C on the Macbook to USB-C on the screen) and not via HDMI and still with a Macbook adapter. There are problems here from time to time. Then connect the external HDD or SSD via USB-A to the monitor or (with or without adapter) directly to the Macbook.

I connected my M2 via HDMI and it runs perfectly. This model also has a Displayport or, as already mentioned, USB-C. The PA27AC model is said to have scaling problems on MacOS, which the PA279CRV does not have.

Yes, its there. The screen is nice, but not very stable in the viewing angle. If you sit in front of the panel, you can see a slight shift to red on the left and right screenboder. It is not noticeable when working, but if you look very closely then it is noticeable.