Yes you can, according to the specs your computer has 3 USB C Thunderbolt 4 ports with DisplayPort 2.1. Therefore should work seamlessly.

Yes, a driver is available for Windows 11, though whether it is strictly required depends on your specific use case and connection method. ASUS provides the ASUS_MQ149CD_WHQL_Driver for Windows 11 64-bit systems. However, the monitor can function with basic display output through standard Windows drivers if you connect via Mini HDMI or USB-C without needing the proprietary driver installed. If you need to use advanced features such as multiple display modes (extend mode, split mode, or independent mode), the OSD menu controls, or automatic screen rotation, the ASUS driver and DisplayWidget Center software may be necessary. For a basic work setup with standard display functionality, the monitor may operate without the proprietary driver, but I'm not completely certain about this answer. The information I have does not fully address whether all features work optimally without installation. I recommend consulting ASUS support or your corporate IT department to confirm compatibility with your specific setup and restrictions.