If not, is there a possibility (software) that makes it possible?

Yes, this monitor can be split into two screens to work separately 👍

Yes, the monitor can be split into two separate screens with different inputs. E.g. one side Displayport and the other side HDMI input.

Unless you take a chainsaw... you can display two separate computers where the display is limited to 60Hz, then it's possible to manage screen sharing under Windows by separating the screen into two or more depending on the applications you want. I haven't found any software yet that would make this possible.