The "Wireless Carplay Dongle (USB Type C, USB-A)" from PowerGuard could work with a Mercedes C-Class w205 from 2016, but there are some important points to consider:

## Compatibility
- The dongle typically require that the vehicle already has Apple CarPlay installed, either from the factory or through an aftermarket upgrade. For Mercedes C-Class w205 models from 2016, these vehicles often come with the NTG 5 or NTG 5.5 infotainment system.

## Requirements
- If your Mercedes C-Class w205 from 2016 already supports Apple CarPlay via a USB port, then the Wireless Carplay Dongle might work. However, it is important to check that the specific dongle is compatible with the NTG 5 or NTG 5.5 system.

## Installation and operation
- The installation of such dongles usually requires that AUX or other necessary functions are enabled in the vehicle. It is also important to follow the manufacturer's specific instructions for installation and configuration.

To ensure that the dongle is compatible with your vehicle, I recommend checking the manufacturer's specific compatibility requirements and contacting PowerGuard directly if necessary.