The compatibility of the ASUS SimPro Dock 2 with the ASUS ROG Strix G16 depends on several factors, including the ports and protocols supported by the laptop.

- The ASUS SimPro Dock 2 is compatible with laptops that support the alternative USB-C mode or Thunderbolt protocols via the Type-C port.
- The ROG Strix G16 must have a USB-C port that supports these protocols to be compatible with the dock.

You'll need to check the specifications of the ROG Strix G16 to confirm whether it has a USB-C port that supports alternative USB-C or Thunderbolt mode. If so, the SimPro Dock 2 should work correctly with your laptop.