The AOC AD110D0 monitor arm is designed to support two monitors with a VESA mount. However, there is no specific information that it is explicitly designed for the combination of a 27-inch and a 24-inch monitor. However, the arm supports monitors with a weight class that is typically suitable for monitors of this size.

To ensure that the arm can support both monitors, you should check the following points:
- VESA compatibility: make sure both monitors have VESA mounts.
- Weight restrictions: Check the weight limitations of the arm and compare them to the weights of your monitors.
- Mounting compatibility: Ensure that the 24-inch monitor can be easily mounted on the arm without compromising stability.

It is advisable to consult the technical specifications of the product and the manufacturer's instructions to ensure optimal and safe use.