The main difference between the De'Longhi ECAM220.60.B and the ECAM220.80.SB lies in the milk frothing system. The ECAM220.60.B does not have an automatic milk frothing system, while the ECAM220.80.SB has an automatic milk frothing system. Both models offer similar basic functions such as espresso and coffee at the touch of a button, but the ECAM220.80.SB makes it possible to prepare cappuccino and other milk drinks automatically.