The Tacx NEO 2T Smart Trainer is generally compatible with many bikes, but there are a few things you should consider to ensure that your Trek Emonda can be installed without any problems.

### Axle compatibility
- The NEO 2T supports various axle types, including Quick-Release (QR), non-Boost (142mm) and Boost (148mm) thru-axle. However, it is important to note that it does not support Super Boost axles (157mm).

### Cassette compatibility
- The trainer comes with a Shimano HG freehub, which means you must use a cassette with Shimano HG or SRAM NX 11-50 HG compatible cog spacing. You may need to purchase a cassette separately or use the one from your bike if it is compatible.

### Installation
- Installing your bike on the trainer involves removing the rear wheel and attaching the trainer to the rear axle. There are special adapter kits for thru-axle that come with the trainer if necessary.

If your Trek Emonda has one of the supported axle types and a compatible cassette, installation should be straightforward. However, it is advisable to check the specific requirements of your bike before installation and obtain the necessary adapters or cassettes if necessary.