This 16GB RAM is 100% compatible with Dell PowerEdge R7415. Information on memory configuration: The following technical specifications should be considered in advance: RDIMM and RDIMM 3DS (Registered DIMM) or LRDIMM and LRDIMM 3DS (Load Reduced DIMM) RAM can be installed in the device. LRDIMM memory is recommended when large memory capacities are required. RDIMM and RDIMM 3DS memory modules cannot be mixed with LRDIMM and LRDIMM 3DS memory. If a memory upgrade is to be made with the existing RAM, it must be checked which base memory technology (RDIMM / LRDIMM) is present. When using a multiprocessor system, the memory slots should always be populated identically for each CPU. A higher memory clock of the memory module automatically adjusts to the memory clock specified by the system. This can especially be the case with larger capacities.