This 32GB memory is 100% compatible with Asus ESC4000A-E12 (K14PG-U12). The following technical specifications should be considered in advance: RDIMM and RDIMM 3DS (Registered DIMM) or LRDIMM and LRDIMM 3DS (Load Reduced DIMM) RAM memory can be installed in the unit. LRDIMM memory is recommended when large memory capacities are to be achieved. RDIMM and RDIMM 3DS memory modules cannot be mixed together with LRDIMM and LRDIMM 3DS RAM. If a memory expansion is to be made with the RAM memories already present, it must be checked which basic memory technology (RDIMM / LRDIMM) is present. Memory slots for which there is no processor must not be populated.