This 32GB RAM is 100% compatible with HP ProLiant SL250s Gen8 (G8).

Information on memory configuration: The following technical specifications should be considered in advance: RDIMM (Registered DIMM) or LRDIMM (Load Reduced DIMM) RAM can be installed in the device. LRDIMM memory is recommended for achieving large memory capacities. RDIMM memory modules cannot be mixed with LRDIMM memory. If a memory upgrade is to be made with the existing RAM, it must be checked which memory technology (RDIMM / LRDIMM) is present. Memory slots without a processor should not be populated. A higher memory clock speed of the memory module will automatically adjust to the memory clock speed set by the system. This can especially be the case with larger capacities. When using 4Rank (4Rx..) RDIMM memory, only 2 out of 3 memory slots per memory channel can be populated.