This 64GB RAM is 100% compatible with Intel S2600WF0R. Our memory team is happy to assist you in choosing the right RAM and configuring your server. The following technical considerations should be noted in advance: You can use RDIMM memory or LRDIMM memory. LRDIMM memory is particularly recommended when large memory capacities are required. Registered DIMM and Load Reduced LRDIMM memory modules should not be mixed. Therefore, when upgrading, you should know which memory is already present or upgrade completely to either RDIMM or LRDIMM memory. Memory slots without a processor present must not be populated. Higher memory frequencies may adapt to other memory clock rates in the system environment and support correspondingly slower clock rates.