This 128GB RAM is 100% compatible with the Supermicro SuperServer 2028TR-H72R. What memory configuration is possible? Our memory team is happy to assist you in choosing the right RAM and configuring your device. In general, your system may be equipped with processors from the E5-2600 v3 or E5-2600 v4 series. Accordingly, the memory can be configured to match. The RAM can be selected as either RDIMM (Registered DIMM) or LRDIMM (Load Reduced DIMM). RDIMM and LRDIMM cannot be mixed. Therefore, when upgrading, you should know which memory is already installed or completely upgrade with LRDIMM memory. Only the memory slots corresponding to the respective CPU can be used.