You can use two kits of the Trident Z5 NEO RGB (2 x 16GB, 6000 MHz) in an ASUS ROG Strix B850-E Gaming WiFi, as the board has four DIMM slots and supports DDR5 RAM. However, you should make sure that the clock frequency and CAS latency are compatible with your processor. Support for AMD EXPO could also be helpful to optimise performance. It is advisable to check the specifications of your processor and motherboard to ensure that all components work together optimally.

Also works under b850 important BIOS update beforehand

The hardware is the same in both sticks (identical RAM chips). But for AMD systems these are better because it comes with EXPO profiles that are designed for AMD mainboards and processors. The other sticks (item no. 18510367), on the other hand, have XMP profiles (instead of EXPO), and these are made for Intel mainboards and processors. Although AMD systems can also handle XMP profiles, if an identical RAM kit with EXPO profile is available, this is the better choice.

Compare the product number F5-6000J3038F16GX2-TZ5N vs F5-6000J3038F16GX2-TZ5NR (the R at the end is for the RGB variant), same timings and same voltage DDR5-6000 CL30-38-38-96 1.35V