The hard drive has a USB-C connection and can therefore be connected directly to the Macbook. The connector for TB4 and USB-C is the same. You don't need a different cable.

Hoi - it depends on what exactly you want to use it for and where/how you want to use it permanently. The case is certainly not problematic, except for the temperature range (up to 35°C? I easily reach that in various places around my equipment in winter...), the power supply unit is more likely, but will probably last longer. That leaves the hard disks: Ultrastar disks from WD are installed (could well be this one: https://www.westerndigital.com/de-de/products/internal-drives/data-center-drives/ultrastar-dc-hc550-hdd#0F38459) - and here are the specs of this disk: https://documents.westerndigital.com/content/dam/doc-library/en_us/assets/public/western-digital/product/data-center-drives/ultrastar-dc-hc500-series/data-sheet-ultrastar-dc-hc550.pdf These are data centre scale-out disks, where size/rapping is important... yes also the availability... but in the data centre sector redundancy is taken into account (raid levels with spares etc., shelf replacement, disk spares cold etc.). Thus, even ;) Continuous use? Tell me... LG

Yes, according to the manufacturer's page, the G-Drive is compatible from macOS 10.12+ and is already formatted at the factory so that it does not need to be reformatted for macOS 👍 https://shop.westerndigital.com/de-de/products/external-drives/sandisk-pro-g-drive-usb-3-1-hdd#SDPH91G-004T-MBAAD