Yes but there is no guarantee that it will run cleanly: https://www.golem.de/news...
I use the 2080 Ti with the Asus LC49RG and this works flawlessly without image errors.

"can't" but there is a list of Nvidia certified Freesync monitors that work with nvidia cards from the 10XX series onwards. Read more: https://www.pc-magazin.de/ratgeber...