yes, I have this configuration. And I noticed the following: my printer, which only establishes a 0.1Gbit/s connection, is not recognised on this port. But this is not a real problem, there are 8 other ports for this.

Works without problems

I can't answer that definitively. It depends mainly on Zyxel whether they allow third-party modules or not. At least the Ubiquiti module in a Dell S-4112F switch worked for me without any problems.