Samsung Electronics GmbH
Hello,
Thank you for your enquiry.
For this SSD, your PlayStation 4 requires a SATA interface as well as a free mounting slot in the 2.5 inch form factor.
If in doubt, please contact the manufacturer of your device.
Kind regards from Schwalbach
Your Samsung Service Team

I suppose so, if it has a SATA connector and you know how to install the operating system. To be tested.