Compatible with the following mainboards from Asus:

ROG RAMPAGE VI EXTREME
PRIME X299-DELUXE
PRIME X299-A
TUF X299 MARK 1
TUF X299 MARK 2
PRIME Z370-A
MAXIMUS IX HERO
PRIME Z270-A
PRIME Z270-AR
TUF Z270 Mark 1
Z170-PREMIUM
Z170-DELUXE
Z170-PRO
Z170-A
Z170-AR
SABERTOOTH Z170 MARK 1
SABERTOOTH Z170 S
MAXIMUS VIII EXTREME
MAXIMUS VIII HERO
MAXIMUS VIII RANGER
X99-DELUXE II
X99-DELUXE
X99-DELUXE/U3.1
X99-PRO/USB 3.1
X99-PRO
X99-A/USB 3.1
X99-A
X99-A II
X99-E
SABERTOOTH X99
RAMPAGE V EXTREME/U3.1
RAMPAGE V EXTREME
X99-E WS/USB3.1
X99-E WS

A TB header is required on the mainboard.