This 16GB RAM is 100% compatible with the Tyan S7045. What memory configuration is possible? Our memory team is happy to assist you in choosing the right RAM and configuring your server. ECC DIMM, Registered DIMM, and Load Reduced LRDIMM memory modules should not be mixed. Therefore, when upgrading, you should know which memory is already installed or completely upgrade to RDIMM memory. Principles of memory configuration: Only the memory slots where the respective CPU is present can be used. Memory configuration for good system performance: Distribute the memory evenly across the memory slots and evenly across the CPUs. If more than one CPU is present, the memory should be identically configured per CPU (mirrored to the other CPU).