I don't have exactly the same board, but a similar one: ASUS ROG Crosshair VIII Hero WI-FI. I have the same RAM, but 4 modules with 16GB each, so a total of 64GB. With this setup, the fan fits in well with a few mm of air. You can also put the fan a little higher, then there is a little more room to manoeuvre. With two modules, you could leave the backmost one empty, then you shouldn't have a problem in my opinion - unless the X570-E was built differently.

i also have an asus rog strix x570-e and also the dark rock pro 4 cooler. i would like to fill the 4 banks with ram. i mean i read that the ram must not have more than 42mm height because otherwise there is a problem with the cooler.
I would also like to install a g skill ram, but I don't want to buy a ram that won't fit under the cooler.
does anyone have a system at home where all 4 banks are filled and with the same cooler?